P.B. Mthembi Medical Laboratories is an independent Clinical Pathology service that is committed to good laboratory and professional practice. It has been formed as a private company, registered with the board of healthcare funders (BHF) and the Companies and Intellectual Property Commission (CIPC). The laboratory was founded by P.B. Mthembi and is 100% black-owned. Its main aim is to excel in previously untouched entrepreneurial spaces. The Lab offers clinical pathology services on-site and specialized services are outsourced to other facilities; however, these will be managed by P.B. Mthembi Medical Laboratories. Only facilities that offer a competitive quality service with a good turnaround time will be considered. Tests that are performed in-house have guaranteeing results within 12 hours.

P.B. Mthembi Medical Laboratories is located inside Mamelodi Gardens Health Clinic – which is home to a general practitioner, a dental practice, a psychology practice and an optometrist. Before the establishment of the laboratory, when doctors needed pathology services, they had to send their patients or specimens to an off-site laboratory, a 30 minute to an hour drive away from Mamelodi.