Situated in Mekʼelē, 400 m from Emperor Yohannes Museum Mekelle, Desta International Hotel features air-conditioned accommodation and a bar. Among the facilities of this property are a restaurant, a 24-hour front desk and room service, along with free WiFi. The hotel has a garden and provides a terrace.

The rooms in the hotel are fitted with a flat-screen TV. At Desta International Hotel, rooms come with a private bathroom with a bath.

A continental breakfast is available each morning at the accommodation.

The Hawetti Marter Memorial Monument is 2.8 km from Desta International Hotel, while Mekelle University is 3 km from the property. The nearest airport is Alula Aba Airport, 7 km from the hotel.